Treatments

Kidney Transplant: A Complete Guide

For most people with kidney failure, a transplant offers the best quality of life and long-term survival. Here is what the journey looks like.

A kidney transplant places a single healthy kidney from a donor into your body to take over the work of your failed kidneys. It is widely considered the gold-standard treatment for kidney failure — offering more freedom, a less restricted diet, and better long-term outcomes than dialysis for suitable patients.

Step 1 — Evaluation

Before a transplant, a thorough assessment checks that surgery is safe and likely to succeed. This includes blood and tissue-typing tests, heart and infection screening, and a discussion of your overall health. Not everyone is a candidate, and the team will guide you honestly.

Step 2 — Finding a donor

Living donor

A healthy relative or friend donates one kidney. Living-donor kidneys usually work immediately and last longer. Donors can live full, healthy lives with one kidney.

Deceased donor

A kidney from someone who has died and chosen to donate. Patients join a waiting list and are matched by blood group, tissue type and other factors.

When blood groups differ, specialised ABO-incompatible protocols can sometimes still make a living-donor transplant possible.

Video explainer coming soon

An overview of how a kidney transplant is performed.

Step 3 — The surgery

The operation usually takes 3–4 hours. The new kidney is placed in the lower abdomen; your own kidneys are generally left in place. Most patients stay in hospital for about a week and notice improved energy as the new kidney begins to work.

Step 4 — Life after transplant

A transplant is a treatment, not a cure — it needs lifelong care to protect the new kidney:

  • Immunosuppressant medicines every day to prevent rejection. Never skip doses.
  • Regular clinic visits and blood tests, frequent at first, then spaced out.
  • Infection precautions, since immune-suppressing drugs raise infection risk.
  • Healthy lifestyle — a balanced diet, activity, no smoking, and blood-pressure control.

Watch for rejection

Report fever, reduced urine, pain over the transplant, or sudden weight gain promptly. Early rejection is often treatable when caught quickly.

References & Further Reading

  1. National Kidney Foundation. "Kidney Transplant." kidney.org
  2. KDIGO Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation. kdigo.org
  3. NIDDK, National Institutes of Health. "Kidney Transplant." niddk.nih.gov

This article is for general education only and does not replace personalised medical advice. Transplant suitability must be assessed by a qualified transplant team.

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